United States, Nevada, Las Vegas, DelveInsight’s ‘Diffuse Cutaneous Systemic Sclerosis Pipeline Insight 2023‘ report provides comprehensive global coverage of available, marketed, and pipeline Diffuse Cutaneous Systemic Sclerosis therapies in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the Diffuse Cutaneous Systemic Sclerosis pipeline domain.
Key Takeaways from the Diffuse Cutaneous Systemic Sclerosis Pipeline Report
Diffuse Cutaneous Systemic Sclerosis Overview
Diffuse cutaneous systemic sclerosis (dcSSc) is a subtype of systemic scleroderma (systemic sclerosis) and is characterized by skin hardening (fibrosis) and problems in many organs of the body. The prevalence is estimated at about 1/25,000 adults. Women are predominantly affected. The disease usually manifests at between 40 and 50 years of age. Pediatric onset can occur but is extremely rare. Raynaud’s phenomenon is often the first sign of the disease. The other signs usually appear a few months later. Skin hardening first occurs on the fingers and face, but rapidly becomes generalized. Telangiectasias are sometimes present on the thorax, face, lips, tongue, and fingers. Tendon friction rubs are observed. Esophageal dysmotility is common and provokes gastroesophageal reflux and sometimes dysphagia. Gastrointestinal malabsorption and dysmotility may also be present and are associated with weight loss, vomiting, diarrhea or occlusion. Dry mouth and dental involvement can occur. Arthralgias and acroosteolysis are frequent.
Diffuse Cutaneous Systemic Sclerosis Pipeline Analysis: Drug Profile
FCR 001: Talaris Therapeutics
FCR001 is an investigational, allogeneic cell therapy developed by Talaris Therapeutics to induce or restore patients’ immune tolerance. FCR001 builds on over 30 years of research by the company’s founder, Dr. Suzanne Ildstad, into the means by which durable immune tolerance can be induced in a patient who receives a transplanted organ or can be restored in patients with certain immune-mediated or blood disorders. FCR001 has received both Orphan Drug Designation and Regenerative Medicine Advanced Therapy (RMAT) designation from the U.S. Food and Drug Administration. Currently, the drug is being developed in the Phase I/II stage of clinical trial evaluation for the treatment of Diffuse Cutaneous Systemic Sclerosis.
Discover more about the emerging Diffuse Cutaneous Systemic Sclerosis drugs @ Diffuse Cutaneous Systemic Sclerosis Treatment Drugs
Diffuse Cutaneous Systemic Sclerosis Key Companies
Diffuse Cutaneous Systemic Sclerosis Pipeline Therapies
Diffuse Cutaneous Systemic Sclerosis Pipeline Therapeutics Assessment
Scope of the Diffuse Cutaneous Systemic Sclerosis Pipeline Report
Find out more about the Diffuse Cutaneous Systemic Sclerosis treatment options in development @ Diffuse Cutaneous Systemic Sclerosis Clinical Trials
Table of Contents
1. Introduction
2. Executive Summary
3. Overview
4. Pipeline Therapeutics
5. Late-Stage Products (Phase III)
6. Mid-Stage Products (Phase II)
7. Early Stage Products (Phase I/II)
8. Preclinical Stage Products
9. Discovery Stage Products
10. Therapeutic Assessment
11. Inactive Products
12. Collaborations Assessment- Licensing / Partnering / Funding
13. Unmet Needs
14. Market Drivers and Barriers
15. Appendix
16. About DelveInsight
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